K-562 cells were subjected to SDS PAGE followed by western blot with FNab01691(CHST11 antibody) at dilution of 1:500
背景介绍
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine(GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.