HepG2 cells were subjected to SDS PAGE followed by western blot with FNab01698(CHST9 antibody) at dilution of 1:500
背景介绍
Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine(GalNAc) residues in both N-glycans and O-glycans. Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Has a higher activity toward carbonic anhydrase VI than toward lutropin. Only active against terminal GalNAcbeta1,GalNAcbeta. Isoform 2, but not isoform 1, is active toward chondroitin.