HeLa cells were subjected to SDS PAGE followed by western blot with FNab01861(GJA1 antibody) at dilution of 1:1000
IP Result of anti-Connexin-43 (IP: FNab01861, 4ug; Detection: FNab01861 1:1000) with mouse heart tissue lysate 3200ug.
Immunohistochemistry of paraffin-embedded mouse heart using FNab01861(GJA1 antibody) at dilution of 1:100
Immunofluorescent analysis of ( -20℃ Ethanol ) fixed HeLa cells using FNab01861 at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
背景介绍
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract(By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles(By similarity).