HeLa cells were subjected to SDS PAGE followed by western blot with FNab01940(CPSF6 antibody) at dilution of 1:100
IP Result of anti-CPSF6 (IP:FNab01940, 4ug; Detection:FNab01940 1:300) with HeLa cells lysate 3200ug.
Immunohistochemistry of paraffin-embedded human kidney using FNab01940(CPSF6 antibody) at dilution of 1:50
背景介绍
Component of the cleavage factor Im complex(CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping.