HL-60 cells were subjected to SDS PAGE followed by western blot with FNab02090(CX3CR1 antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human tonsillitis using FNab02090(CX3CR1 antibody) at dilution of 1:50
背景介绍
Receptor for the CX3C chemokine fractalkine(CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions(PubMed:9390561, PubMed:23125415). Acts as coreceptor with CD4 for HIV-1 virus envelope protein(in vitro)(PubMed:9726990). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1(PubMed:14607932).