Jurkat cells were subjected to SDS PAGE followed by western blot with FNab02099(CXCR1 antibody) at dilution of 1:300
IP Result of anti-CXCR1 (IP:FNab02099, 4ug; Detection:FNab02099 1:500) with Jurkat cells lysate 4000ug.
背景介绍
Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA(GRO) with a low affinity.