human liver tissue were subjected to SDS PAGE followed by western blot with FNab02170(CYP4F11 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human liver cancer using FNab02170(CYP4F11 antibody) at dilution of 1:100
背景介绍
Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1(phylloquinone), and menaquinone-4(MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation(PubMed:24138531). Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3-hydroxyarachidonate, and 3-hydroxystearate(PubMed:18065749, PubMed:19932081). Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine(PubMed:15364545).