Drebrin-like protein|Cervical SH3P7|Cervical mucin-associated protein|Drebrin-F|HPK1-interacting protein of 55 kDa (HIP-55)|SH3 domain-containing protein 7|DBNL|CMAP|SH3P7 antibody
货号:
FNab02257
反应性:
Human, Mouse, Rat
宿主:
Rabbit
验证实验:
ELISA, WB, IHC, IF, IP
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥1750
50μg
RMB ¥1050
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
DBNL antibody
货号
FNab02257
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
drebrin-like
别称
Drebrin-like protein|Cervical SH3P7|Cervical mucin-associated protein|Drebrin-F|HPK1-interacting protein of 55 kDa (HIP-55)|SH3 domain-containing protein 7|DBNL|CMAP|SH3P7 antibody
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02257(DBNL antibody) at dilution of 1:1000
IP Result of anti-DBNL (IP:FNab02257, 4ug; Detection:FNab02257 1:1000) with mouse brain tissue lysate 2640ug.
Immunohistochemistry of paraffin-embedded human breast cancer using FNab02257(DBNL antibody) at dilution of 1:100
背景介绍
Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes(By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.