Immunohistochemistry of paraffin-embedded human prostate cancer using FNab02323(DEDD antibody) at dilution of 1:50
背景介绍
A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro(By similarity).