DnaJ homolog subfamily A member 1|DnaJ protein homolog 2|HSDJ|Heat shock 40 kDa protein 4|Heat shock protein J2 (HSJ-2)|Human DnaJ protein 2 (hDj-2)|DNAJA1|DNAJ2|HDJ2|HSJ2|HSPF4 antibody
货号:
FNab02439
反应性:
Human, Mouse
宿主:
Rabbit
验证实验:
ELISA, WB, IHC
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥2100
50μg
RMB ¥1260
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
DNAJA1 antibody
货号
FNab02439
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
DnaJ(Hsp40) homolog, subfamily A, member 1
别称
DnaJ homolog subfamily A member 1|DnaJ protein homolog 2|HSDJ|Heat shock 40 kDa protein 4|Heat shock protein J2 (HSJ-2)|Human DnaJ protein 2 (hDj-2)|DNAJA1|DNAJ2|HDJ2|HSJ2|HSPF4 antibody
mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab02439(DNAJA1 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human colon cancer using FNab02439(DNAJA1 antibody) at dilution of 1:50
背景介绍
Co-chaperone for HSPA8/Hsc70(PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A(in vitro)(PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis(PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV(PubMed:24512202).