HeLa cell were subjected to SDS PAGE followed by western blot with FNab02490(DNTTIP1 Antibody) at dilution of 1:500
IP Result of anti-DNTTIP1 (IP:FNab02490 4ug; Detection:FNab02490 1:300) with HeLa cells lysate 1200ug.
背景介绍
Increases DNTT terminal deoxynucleotidyltransferase activity(in vitro)(PubMed:11473582). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.