Dipeptidyl peptidase 4|ADABP|Adenosine deaminase complexing protein 2 (ADCP-2)|Dipeptidyl peptidase IV (DPP IV)|T-cell activation antigen CD26|TP103|Dipeptidyl peptidase 4 membrane form Alternative names: Dipeptidyl peptidase IV membrane form|Dipeptidyl peptidase 4 soluble form Alternative names: Dipeptidyl peptidase IV soluble form|DPP4|ADCP2|CD26 antibody
货号:
FNab02520
反应性:
Human, Mouse, Rat
宿主:
Rabbit
验证实验:
ELISA, WB, IHC, IF
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥2100
50μg
RMB ¥1260
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
DPP4 antibody
货号
FNab02520
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
dipeptidyl-peptidase 4
别称
Dipeptidyl peptidase 4|ADABP|Adenosine deaminase complexing protein 2 (ADCP-2)|Dipeptidyl peptidase IV (DPP IV)|T-cell activation antigen CD26|TP103|Dipeptidyl peptidase 4 membrane form Alternative names: Dipeptidyl peptidase IV membrane form|Dipeptidyl peptidase 4 soluble form Alternative names: Dipeptidyl peptidase IV soluble form|DPP4|ADCP2|CD26 antibody
U-937 cells were subjected to SDS PAGE followed by western blot with FNab02520(DPP4 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab02520(DPP4 antibody) at dilution of 1:100
背景介绍
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor(TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix(ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.