HepG2 cells were subjected to SDS PAGE followed by western blot with FNab02573( DVL2 Antibody) at dilution of 1:1000
IP Result of anti-DVL2 (IP: FNab02573, 4ug; Detection: FNab02573 1:1000) with MCF-7 cells lysate 3200ug.
Immunofluorescent analysis of HepG2 cells using FNab02573 (DVL2 antibody) at dilution of 1:50 and Rhodamine-Goat anti-Rabbit IgG
背景介绍
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes(By similarity).