mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02777(ENSA antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using FNab02777(ENSA Antibody) at dilution of 1:50
背景介绍
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A(PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D(PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase(By similarity). Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor(ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.