human heart tissue were subjected to SDS PAGE followed by western blot with FNab02837(ERCC6L antibody) at dilution of 1:800
背景介绍
DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.