mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab02890(EXD2 antibody) at dilution of 1:300
IP Result of anti-EXD2 (IP:FNab02890, 3ug; Detection:FNab02890 1:300) with mouse lung tissue lysate 5160ug.
Immunohistochemistry of paraffin-embedded human testis using FNab02890(EXD2 antibody) at dilution of 1:50
背景介绍
Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.