Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03078(FERMT3 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human lymphoma using FNab03078(FERMT3 antibody) at dilution of 1:50
背景介绍
Plays a central role in cell adhesion in hematopoietic cells(PubMed:19234463, PubMed:26359933). Acts by activating the integrin beta-1-3(ITGB1, ITGB2 and ITGB3)(By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells(PubMed:19234460). Required for activation of integrin beta-2(ITGB2) in polymorphonuclear granulocytes(PMNs)(By similarity). Isoform 2 may act as a repressor of NF-kappa-B and apoptosis.