Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03532(GNAI2 antibody) at dilution of 1:1000
IP Result of anti-GNAI2 (IP: FNab03532, 4ug; Detection: FNab03532 1:1000) with mouse kidney tissue lysate 3000ug.
Immunohistochemistry of paraffin-embedded rat kidney tissue slide using FNab03532(GNAI2 Antibody) at dilution of 1:50
Immunofluorescent analysis of Hela cells, using FNab03532(GNAI2 Antibody) at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG.
背景介绍
Guanine nucleotide-binding proteins(G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. Isoform sGi2: Regulates the cell surface density of dopamine receptors DRD2 by sequestrating them as an intracellular pool.