HEK-293T cells were subjected to SDS PAGE followed by western blot with FNab03585(GPN1 antibody) at dilution of 1:500
背景介绍
Small GTPase required for proper nuclear import of RNA polymerase II(RNAPII)(PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import(PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation(PubMed:17643375). May be involved in nuclear localization of XPA(PubMed:11058119).