产品
本公司产品仅供体外研究使用，不用于临床诊断
GSK3B antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥1900 |
| 50μg | RMB ¥1140 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- GSK3B antibody
- 货号
- FNab03676
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- glycogen synthase kinase 3 beta
- 别称
- Glycogen synthase kinase-3 beta (GSK-3 beta)|Serine/threonine-protein kinase GSK3B|GSK3B antibody
- UniProt ID
- P49841
- 分子量
- 50 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF, IP
- 建议稀释比例
- WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
验证图片
mouse ovary tissue were subjected to SDS PAGE followed by western blot with FNab03676(GSK3B antibody) at dilution of 1:1000
IP Result of anti-GSK3B (IP: FNab03676, 3ug; Detection: FNab03676 1:500) with HeLa cells lysate 800ug.
Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab03676(GSK3B Antibody) at dilution of 1:50
Immunofluorescent analysis of HeLa cells using FNab03676 (GSK3B antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- 背景介绍
- Glycogen synthase kinase-3(GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Researches showed that the crystal structure of human GSK3B, expressed in insect cells, at 2.8-angstrom resolution .This antibody recognize the C-terminal of GSK3B.
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