HeLa cells were subjected to SDS PAGE followed by western blot with FNab03716(GTF2IRD1 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human heart using FNab03716(GTF2IRD1 antibody) at dilution of 1:100
背景介绍
May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer(USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8(By similarity).