HeLa cells were subjected to SDS PAGE followed by western blot with FNab03717(GTF3C4 antibody) at dilution of 1:1000
IP Result of anti-GTF3C4 (IP:FNab03717, 3ug; Detection:FNab03717 1:800) with HeLa cells lysate 875ug.
背景介绍
Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated(VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity(HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.