A375 cells were subjected to SDS PAGE followed by western blot with FNab04000(HPS4 antibody) at dilution of 1:200
IP result of anti-HPS4 (FNab04000 for IP and Detection) with HeLa cell lysate.
Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab04000(HPS4 Antibody) at dilution of 1:50
背景介绍
Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor(GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38(PubMed:23084991).