SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab04011(HRH2 antibody) at dilution of 1:500
背景介绍
The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase(PKC) signaling pathway(By similarity).