mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab04055(HSPA1L Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab04055(HSPA1L antibody) at dilution of 1:100
背景介绍
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage(By similarity). Positive regulator of PARK2 translocation to damaged mitochondria.