Interferon-induced transmembrane protein 1|Dispanin subfamily A member 2a (DSPA2a)|Interferon-induced protein 17|Interferon-inducible protein 9-27|Leu-13 antigen|IFITM1|CD225|IFI17 antibody
货号:
FNab04140
反应性:
Human
宿主:
Rabbit
验证实验:
ELISA, WB, IHC, IP
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥2100
50μg
RMB ¥1260
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
IFITM1 antibody
货号
FNab04140
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
interferon induced transmembrane protein 1(9-27)
别称
Interferon-induced transmembrane protein 1|Dispanin subfamily A member 2a (DSPA2a)|Interferon-induced protein 17|Interferon-inducible protein 9-27|Leu-13 antigen|IFITM1|CD225|IFI17 antibody
K-562 cells were subjected to SDS PAGE followed by western blot with FNab04140(IFITM1 antibody) at dilution of 1:500
IP Result of anti-IFITM1 (IP:FNab04140, 4ug; Detection:FNab04140 1:500) with ROS1728 cells lysate 3200ug.
Immunohistochemistry of paraffin-embedded human lymphoma using FNab04140(IFITM1 antibody) at dilution of 1:50
背景介绍
IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus(SARS-CoV), Marburg virus(MARV), Ebola virus(EBOV), Dengue virus(DNV), West Nile virus(WNV), human immunodeficiency virus type 1(HIV-1) and hepatitis C virus(HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation.