Interleukin-1 receptor type 2 (IL-1R-2 antibody, IL-1RT-2 antibody, IL-1RT2)|CD121 antigen-like family member B|CDw121b|IL-1 type II receptor|Interleukin-1 receptor beta (IL-1R-beta)|Interleukin-1 receptor type II|Interleukin-1 receptor type 2 antibody, membrane form (mIL-1R2 antibody, mIL-1RII)|Interleukin-1 receptor type 2 antibody, soluble form (sIL-1R2 antibody, sIL-1RII)|IL1R2|IL1RB antibody
货号:
FNab04242
反应性:
Human
宿主:
Rabbit
验证实验:
ELISA, WB
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥2100
50μg
RMB ¥1260
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
IL1R2 antibody
货号
FNab04242
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
interleukin 1 receptor, type II
别称
Interleukin-1 receptor type 2 (IL-1R-2 antibody, IL-1RT-2 antibody, IL-1RT2)|CD121 antigen-like family member B|CDw121b|IL-1 type II receptor|Interleukin-1 receptor beta (IL-1R-beta)|Interleukin-1 receptor type II|Interleukin-1 receptor type 2 antibody, membrane form (mIL-1R2 antibody, mIL-1RII)|Interleukin-1 receptor type 2 antibody, soluble form (sIL-1R2 antibody, sIL-1RII)|IL1R2|IL1RB antibody
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04242(IL1R2 antibody) at dilution of 1:1000
背景介绍
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2(membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.