产品
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IL1R2 antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥1900 |
| 50μg | RMB ¥1140 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- IL1R2 antibody
- 货号
- FNab04243
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Protein A+G purification
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- monoclonal
- 亚型
- IgG1
- Clone ID
- 7G9
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- interleukin 1 receptor, type II
- 别称
- Interleukin-1 receptor type 2 (IL-1R-2 antibody, IL-1RT-2 antibody, IL-1RT2)|CD121 antigen-like family member B|CDw121b|IL-1 type II receptor|Interleukin-1 receptor beta (IL-1R-beta)|Interleukin-1 receptor type II|Interleukin-1 receptor type 2 antibody, membrane form (mIL-1R2 antibody, mIL-1RII)|Interleukin-1 receptor type 2 antibody, soluble form (sIL-1R2 antibody, sIL-1RII)|IL1R2|IL1RB antibody
- UniProt ID
- P27930
- 分子量
- 45 kDa
验证实验
- 验证实验
- ELISA, WB, IF
- 建议稀释比例
- WB: 1:500-1:2000; IF: 1:20-1:200
验证图片
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04243(IL1R2 antibody) at dilution of 1:1000
- 背景介绍
- Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2(membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
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