HeLa cells were subjected to SDS PAGE followed by western blot with FNab04302(IMPDH1 antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human ovary tumor slide using FNab04302(IMPDH1 Antibody) at dilution of 1:50
背景介绍
Catalyzes the conversion of inosine 5'-phosphate(IMP) to xanthosine 5'-phosphate(XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.