KN motif and ankyrin repeat domain-containing protein 2|Ankyrin repeat domain-containing protein 25|Matrix-remodeling-associated protein 3|SRC-1-interacting protein (SIP antibody, SRC-interacting protein antibody, SRC1-interacting protein)|KANK2|ANKRD25|KIAA1518|MXRA3|SIP antibody
货号:
FNab04464
反应性:
Human, Mouse, Rat
宿主:
Rabbit
验证实验:
ELISA, IHC, IF
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥1750
50μg
RMB ¥1050
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
KANK2 antibody
货号
FNab04464
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
KN motif and ankyrin repeat domains 2
别称
KN motif and ankyrin repeat domain-containing protein 2|Ankyrin repeat domain-containing protein 25|Matrix-remodeling-associated protein 3|SRC-1-interacting protein (SIP antibody, SRC-interacting protein antibody, SRC1-interacting protein)|KANK2|ANKRD25|KIAA1518|MXRA3|SIP antibody
Immunohistochemistry of paraffin-embedded human colon using FNab04464(KANK2 antibody) at dilution of 1:50
背景介绍
Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway(PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus(PubMed:22371500). May be involved in promotion of cell proliferation(By similarity).