HeLa cells were subjected to SDS PAGE followed by western blot with FNab04575(KIN antibody) at dilution of 1:2000
背景介绍
Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes. May play a role in illegitimate recombination and regulation of gene expression. May participate in mRNA processing. Binds, in vitro, to double-stranded DNA. Also shown to bind preferentially to curved DNA in vitro and in vivo(By similarity). Binds via its C-terminal domain to RNA in vitro.