产品
本公司产品仅供体外研究使用，不用于临床诊断
LDLR antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥1900 |
| 50μg | RMB ¥1140 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- LDLR antibody
- 货号
- FNab04742
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- low density lipoprotein receptor
- 别称
- Low-density lipoprotein receptor (LDL receptor)|LDLR antibody
- UniProt ID
- P01130
- 分子量
- 150-160 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF
- 建议稀释比例
- WB: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:50-1:500
验证图片
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04742(LDLR antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab04742(LDLR Antibody) at dilution of 1:200 heat mediated antigen retrieved with Sodium Citrate buffer(pH6).
Immunofluorescent analysis of ( -20℃ Ethanol ) fixed HeLa cells using FNab04742 (LDLR antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- 背景介绍
- LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits, which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.
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