Protein lin-7 homolog A (Lin-7A antibody, hLin-7)|Mammalian lin-seven protein 1 (MALS-1)|Tax interaction protein 33 (TIP-33)|Vertebrate lin-7 homolog 1 (Veli-1)|LIN7A|MALS1|VELI1 antibody
货号:
FNab04788
反应性:
Human, Mouse, Rat
宿主:
Rabbit
验证实验:
ELISA, WB, IP, IHC
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥2100
50μg
RMB ¥1260
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
LIN7A antibody
货号
FNab04788
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
lin-7 homolog A(C. elegans)
别称
Protein lin-7 homolog A (Lin-7A antibody, hLin-7)|Mammalian lin-seven protein 1 (MALS-1)|Tax interaction protein 33 (TIP-33)|Vertebrate lin-7 homolog 1 (Veli-1)|LIN7A|MALS1|VELI1 antibody
rat brain tissue were subjected to SDS PAGE followed by western blot with FNab04788(LIN7A Antibody) at dilution of 1:1000
IP Result of anti-LIN7A (IP:FNab04788, 3ug; Detection:FNab04788 1:1000) with mouse brain tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab04788(LIN7A Antibody) at dilution of 1:50
背景介绍
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7(LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B(subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter(SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.