产品
本公司产品仅供体外研究使用，不用于临床诊断
MAGEA3 antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥2100 |
| 50μg | RMB ¥1260 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- MAGEA3 antibody
- 货号
- FNab04937
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Protein A+G purification
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- monoclonal
- 亚型
- IgG2a
- Clone ID
- 4E9
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- melanoma antigen family A, 3
- 别称
- Melanoma-associated antigen 3|Antigen MZ2-D|Cancer/testis antigen 1.3 (CT1.3)|MAGE-3 antigen|MAGEA3|MAGE3 antibody
- UniProt ID
- P43357
- 分子量
- 35-55 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:500-1:2000; IHC: 1:50-1:200
验证图片
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04937(MAGEA3 Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab04937(MAGEA3 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
- 背景介绍
- Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
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