human kidney tissue were subjected to SDS PAGE followed by western blot with FNab05118(MAP2K6 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human breast cancer using FNab05118(MAP2K6 antibody) at dilution of 1:100
背景介绍
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein(MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases(ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.