HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab05190(MINA antibody) at dilution of 1:500
IP Result of anti-MINA (IP:FNab05190, 3ug; Detection:FNab05190 1:500) with HEK-293 cells lysate 2120ug.
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab05190(MINA antibody) at dilution of 1:50
背景介绍
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3(H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.