HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab05200(MIXL1 antibody) at dilution of 1:1000
背景介绍
Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression(By similarity).