HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab05277(MOV10 antibody) at dilution of 1:800
IP result of anti-MOV10(IP:FNab05277, 4ug; Detection:FNab05277 1:300) with Hepg2 cells lysate 3000 ug
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab05277(MOV10 antibody) at dilution of 1:50
背景介绍
Probable RNA helicase. Required for miRNA-mediated gene silencing by the RNA-induced silencing complex(RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. (Microbial infection) Required for RNA-directed transcription and replication of the human hepatitis delta virus(HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.