L02 cells were subjected to SDS PAGE followed by western blot with FNab05406(MTM1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human osteosarcoma using FNab05406(MTM1 antibody) at dilution of 1:100
背景介绍
Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate(PI3P) and phosphatidylinositol 3,5-bisphosphate(PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine-and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.