Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05422(MTUS1 antibody) at dilution of 1:500
IP Result of anti-MTUS1 (IP:FNab05422, 4ug; Detection:FNab05422 1:500) with mouse brain tissue lysate 6000ug.
背景介绍
Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.