MCF7 cells were subjected to SDS PAGE followed by western blot with FNab05428(MUC1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab05428(MUC1 antibody) at dilution of 1:50
背景介绍
MUC1 is a type I transmembrane glycoprotein expressed by various epithelial cells of female reproductive tract, lung, breast, kidney, stomach, and pancreas. MUC1 is transcribed as a large precursor gene product, and upon translation, is cleaved in the endoplasmic reticulum, yielding two subunits: the large extracellular N-terminal subunit (MUC1-N, about 120-200 kDa) and the small cytoplasmic C-terminal subunit (MUC1-C, about 23-30 kDa).