Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05501(MYO18A antibody) at dilution of 1:6000
IP Result of anti-MYO18A (IP:FNab05501, 3ug; Detection:FNab05501 1:300) with HeLa cells lysate 3000ug.
背景介绍
May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact.