NACHT antibody, LRR and PYD domains-containing protein 2|Nucleotide-binding site protein 1|PYRIN domain and NACHT domain-containing protein 1|PYRIN-containing APAF1-like protein 2|NLRP2|NALP2|NBS1|PAN1|PYPAF2 antibody
货号:
FNab05758
反应性:
Human, Mouse
宿主:
Rabbit
验证实验:
ELISA, WB, IHC
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥2100
50μg
RMB ¥1260
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
NLRP2 antibody
货号
FNab05758
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
NLR family, pyrin domain containing 2
别称
NACHT antibody, LRR and PYD domains-containing protein 2|Nucleotide-binding site protein 1|PYRIN domain and NACHT domain-containing protein 1|PYRIN-containing APAF1-like protein 2|NLRP2|NALP2|NBS1|PAN1|PYPAF2 antibody
A549 cells were subjected to SDS PAGE followed by western blot with FNab05758(NLRP2 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human placenta using FNab05758(NLRP2 antibody) at dilution of 1:50
背景介绍
Suppresses TNF-and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.