产品
本公司产品仅供体外研究使用，不用于临床诊断
NOTCH3 antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥1750 |
| 50μg | RMB ¥1050 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- NOTCH3 antibody
- 货号
- FNab05800
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- Notch homolog 3
- 别称
- Neurogenic locus notch homolog protein 3 (Notch 3)|Notch 3 extracellular truncation|Notch 3 intracellular domain|NOTCH3 antibody
- UniProt ID
- Q9UM47
- 分子量
- 250-260 kDa, 100 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IP
- 建议稀释比例
- WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500
验证图片
COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab05800(NOTCH3 antibody) at dilution of 1:500
IP Result of anti-NOTCH3 (IP:FNab05800, 4ug; Detection:FNab05800 1:500) with HeLa cells lysate 2400ug.
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab05800(NOTCH3 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
- 背景介绍
- Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs(By similarity).
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