mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab05971(ODF2 antibody) at dilution of 1:500
IP Result of anti-ODF2 (IP:FNab05971, 5ug; Detection:FNab05971 1:500) with mouse testis tissue lysate 8000ug.
Immunohistochemistry of paraffin-embedded human breast cancer using FNab05971(ODF2 antibody) at dilution of 1:50
背景介绍
Seems to be a major component of sperm tail outer dense fibers(ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.