HL-60 cells were subjected to SDS PAGE followed by western blot with FNab06002(ORAI1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab06002(ORAI1 Antibody) at dilution of 1:200
背景介绍
Ca(2+) release-activated Ca(2+)(CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT(PubMed:16582901).