HeLa cells were subjected to SDS PAGE followed by western blot with FNab06157(PARP2 antibody) at dilution of 1:2000
背景介绍
Involved in the base excision repair(BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.