产品
本公司产品仅供体外研究使用，不用于临床诊断
PRKCG antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥1750 |
| 50μg | RMB ¥1050 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- PRKCG antibody
- 货号
- FNab06485
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- protein kinase C, gamma
- 别称
- Protein kinase C gamma type (PKC-gamma)|PRKCG|PKCG antibody
- UniProt ID
- P05129
- 分子量
- 78 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, FC, IP
- 建议稀释比例
- WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500
验证图片
human brain tissue were subjected to SDS PAGE followed by western blot with FNab06485(PRKCG antibody) at dilution of 1:1000
IP Result of anti-PKC gamma (IP:FNab06485, 4ug; Detection:FNab06485 1:500) with mouse brain tissue lysate 2640ug.
Immunohistochemistry of paraffin-embedded human cerebellum tissue slide using FNab06485(PRKCG Antibody) at dilution of 1:200
Immunofluorescent analysis of ( -20℃ Ethanol ) fixed HeLa cells using FNab06485( PRKCG Antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)
- 背景介绍
- Protein kinase C(PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca(2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14(SCA14), an autosomal dominant neurodegenerative disease.
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