产品
本公司产品仅供体外研究使用，不用于临床诊断
PRKCI antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥1750 |
| 50μg | RMB ¥1050 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- PRKCI antibody
- 货号
- FNab06486
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- protein kinase C, iota
- 别称
- Protein kinase C iota type|Atypical protein kinase C-lambda/iota (PRKC-lambda/iota antibody, aPKC-lambda/iota)|nPKC-iota|PRKCI|DXS1179E antibody
- UniProt ID
- P41743
- 分子量
- 68 kDa
验证实验
- 验证实验
- ELISA, IHC, WB, IP
- 建议稀释比例
- WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:50-1:500
验证图片
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06486(PRKCI antibody) at dilution of 1:500
IP Result of anti-PKC iota (IP: FNab06486, 3ug; Detection: FNab06486 1:500) with HeLa cells lysate 2500ug.
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab06486(PRKCI Antibody) at dilution of 1:200
Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using FNab06486 (PKC iota antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- 背景介绍
- Calcium-and diacylglycerol-independent serine/ threonine-protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early secretory pathway. Is necessary for BCR-ABL oncogene-mediated resistance to apoptotic drug in leukemia cells, protecting leukemia cells against drug-induced apoptosis.
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