Pleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8)|Phosphatidylinositol-four-phosphate adapter protein 2 (FAPP-2 antibody, Phosphoinositol 4-phosphate adapter protein 2 antibody, hFAPP2)|Serologically defined breast cancer antigen NY-BR-86|PLEKHA8|FAPP2 antibody
货号:
FNab06537
反应性:
Human, Mouse, Rat
宿主:
Rabbit
验证实验:
ELISA, WB, IHC
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥1900
50μg
RMB ¥1140
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
PLEKHA8 antibody
货号
FNab06537
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
pleckstrin homology domain containing, family A(phosphoinositide binding specific) member 8
别称
Pleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8)|Phosphatidylinositol-four-phosphate adapter protein 2 (FAPP-2 antibody, Phosphoinositol 4-phosphate adapter protein 2 antibody, hFAPP2)|Serologically defined breast cancer antigen NY-BR-86|PLEKHA8|FAPP2 antibody
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06537(PLEKHA8 antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human kidney using FNab06537(PLEKHA8 antibody) at dilution of 1:50
背景介绍
Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network(TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide(GlcCer) from the trans-Golgi network(TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate(PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.